SEC, IEC, HILIC, HIC, RP-HPLC with UD/PDA/FLD/ELSD Detection；
Size variants, charge variants, glycan profiling, surfactant, process impurities, etc.
Enrichment and fractionation of minor product variants for characterization and activity determination
Fragments: CE-SDS, CE-LIF & CZE；
Charge Variants and pI values: icIEF & IEX
2D SDS-PAGE、2D-DIGE
Determination of HCP Population, identification and coverage of HCP antibodies in the ELISA kits
30+ antigens and anti-drug Abs for popular drug targets；
Bioassay cell lines: 40+ tumor cells, 3-tier cell banking system；
Primary functions: direct binding, competition binding, cell inhibition and direct killing activities；
Fc effector functions: C1q, ADCC, CDC & FcRn
Mw, Peptide Map, Disulfide Isoforms, Glycan profiling；
Determination of product variants and degradation hot spots
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